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    A high-speed counter-current chromatography (HSCCC) method was established for the preparative separation of three sesquiterpenoid lactones from Eupatorium lindleyanum DC. The two-phase solvent system composed of n-hexane–ethyl acetate–methanol–water (1:4:2:3, v/v/v/v) was selected. From 540 mg of the n-butanol fraction of Eupatorium lindleyanum DC., 10.8 mg of 3β-hydroxy-8β-[4 ...

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  • USA Chemical Suppliers - Products: 'L', Page: 42

    Lomefloxacin hydrochloride is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections. Cas No. 98079-52-8. Molecular formula C17H20ClF2N3O3.

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  • Lomefloxacin CAS#: 98079-51-7

    It is the onlyquinolone for which once-daily oral dosing suffices. The oralbioavailability of lomefloxacin is estimated to be 95% to98%. Food slows, but does not prevent, its oral absorption.The extent of biotransformation of lomefloxacin is only about5%, and high concentrations of unchanged drug, rangingfrom 60% to 80%, are excreted in the urine.

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    3.Maxaquin (lomefloxacin hydrochloride) US prescribing information. Pfizer Inc. January, 2005. 4.Avelox (moxifloxacin hydrochloride) US prescribing information.

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  • A STABILITY-INDICATING HPTLC METHOD FOR ESTIMATION .

    Lomefloxacin Hydrochloride in sample was confirmed by comparing theRf and spectra of the spot with that of standard. The peak purity of LOM was assessed by comparing the spectra at three different levels, i.e., peak start (S), peak apex (M) and peak end (E) positions of the spot. PRECISION The precision was determined at two levels, i.e.

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  • Enantioseparation of lomefloxacin hydrochloride by high ...

    Oct 15, 2010· In order to determine the purity, the racemic lomefloxacin and fractions from HSCCC were analyzed by HPLC method. Seen from Fig. 5, the Peak 1 is (−)-enantiomer, the Peak 2 is (+)-enantiomer. These results indicate that racemic lomefloxacin hydrochloride is well resolved by HSCCC.

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    In this paper, we reported a new, simple, accurate, and precise extractive spectrophotometric method for the determination of fluoroquinolones (FQs) including ciprofloxacin (CFX), levofloxacin (LFX), and .

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    Lomefloxacin HCl is a fluoroquinolone antibiotic. Target: Antibacterial Lomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of lomefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and ...

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    Summary: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair.

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  • Lomefloxacin (SC47111A) | Bacterial Inhibitor | MedChemExpress

    Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic. - Mechanism of Action & Protocol. As the situation with COVID-19 continues to unfold in every communities, MedChemExpress is responding to the uncertainty caused by this outbreak thoughtfully and cautiously.

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  • Determination of Fluoroquinolones in Pharmaceutical ...

    Several techniques like voltammetry [], flow injection electrogenerated chemiluminescence [], spectrofluorometry [6, 7], spectrophotometry [8, 9], high-performance liquid chromatography [10, 11], and liquid chromatography tandem mass spectrometry [12, 13] have been used for the determination of fluoroquinolones in pharmaceutical and biological products.

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    Lomefloxacin Hydrochloride (98079-52-8) is solid. It is also known as lomefloxacin hcl. it is use in urinary tract infections, bacterial infections and antibiotic Industry.Lomefloxacin Hydrochloride (98079-52-8) is solid. It is also known as lomefloxacin hcl. it is use in urinary tract infections, bacterial infections and antibiotic Industry.

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    The present invention relates to a new moxifloxacin hydrochloride crystal form and a preparation method thereof. The preparation method comprises: adding anhydrous moxifloxacin hydrochloride or moxifloxacin hydrochloride hydrate or a mixture of anhydrous moxifloxacin hydrochloride and moxifloxacin hydrochloride hydrate to a mixed solvent of an alcohol with a carbon number of not more .

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  • Lomefloxacin CAS#: 98079-51-7

    It is the onlyquinolone for which once-daily oral dosing suffices. The oralbioavailability of lomefloxacin is estimated to be 95% to98%. Food slows, but does not prevent, its oral absorption.The extent of biotransformation of lomefloxacin is only about5%, and high .

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    The present invention relates to a new moxifloxacin hydrochloride crystal form and a preparation method thereof. The preparation method comprises: adding anhydrous moxifloxacin hydrochloride or moxifloxacin hydrochloride hydrate or a mixture of anhydrous moxifloxacin hydrochloride and moxifloxacin hydrochloride hydrate to a mixed solvent of an alcohol with a carbon number of not more .

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